SYNTHESES OF 1-DEOXYNOJIRIMYCIN-TREHALAMINE-FUSED AND -LINKED COMPOUNDS AND THEIR BIOLOGICAL ACTIVITIES
1998
Abstract 1-Deoxynojirimycin-trehalamine-fused and -linked compounds ( 10, 19a and 19b ) were synthesized from 1-deoxy-2,3,4,6-tetra- O -benzylnojirimycin and trehazolamine, which was obtained from natural trehazolin as a degradation product. None of these synthetic compounds exceeded 1-deoxynojirimycin in the inhibitory activities towards rat intestinal maltase and yeast α- d -glucosidase.
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