PD59-09 TARGETING STEROID SULFATASE WITH NOVEL INHIBITORS SUPPRESSES CRPC TUMOR GROWTH AND IMPROVES RESPONSE TO ENZALUTAMIDE
2020
INTRODUCTION AND OBJECTIVE:Steroid sulfatase (STS) is a key enzyme that catalyzes the hydrolysis of DHEAS to the biologically active DHEA, which is further metabolized to active androgens that bind...
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