Gαs regulates the post-endocytic sorting of G protein-coupled receptors
2014
Following their internalization, G protein-coupled receptors may continue to signal from endosomes through downstream proteins such as Gαs. Rosciglione et al. reveal that Gαs also regulates the onward trafficking of these receptors from endosomes to lysosomes by interacting with components of the ESCRT complex.
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