The clinical efficacy of simvastatin in the treatment of acute myocardial infarction

Objective To investegate the clinical efficacy of simvastation in patients with acute myocardial infarction(AMI).Methods 156 patients with AMI who received the conventional therapies,such as thrombolysis,antiplatelet and antianginal therapies were randomized into two groups,and 84 patients in the treatment group were given simvastatin 20~40 mg,po,qd,at the same time.Results The rate of survival leave hospital and that of the survival after one year were higher(77.38% vs 62.50%,P0.05;81.67% vs 57.14%,P0.01) and the heart ocurrence rate was lower(60.00% vs 80.95%,P0.05) in one year in the treatment group than that in the control group.Conclusion The clinical efficacy of simvastatin on AMI was satisfactory.