Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner

Enikő Balogh,Andrea Tóth,Gábor Méhes,György Trencsényi,György Paragh,Viktória Jeney

Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)–Dependent and Reactive Oxygen Species–Dependent Manner

2019

Enikő Balogh
Andrea Tóth
Gábor Méhes
György Trencsényi
György Paragh
Viktória Jeney

Objective— Vascular calcification is associated with high risk of cardiovascular events and mortality. Osteochondrogenic differentiation of vascular smooth muscle cells (VSMCs) is the major cellula...

Keywords:

Biochemistry
Vascular smooth muscle
Cell biology
Hypoxia (medical)
Diabetes mellitus
Reactive oxygen species
Biology
Hypoxia-Inducible Factor 1
Myocyte
vascular calcification
Regulation of gene expression
Mitochondrion

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