Membrane cytoskeleton: PIP2 pulls the strings
2000
Abstract A recent application of optical tweezers has shown that plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP 2 ) levels control adhesion of the membrane bilayer to the underlying cytoskeleton, by regulated direct binding of PIP 2 to cytoskeletal proteins and/or indirect effects on cytoskeleton structure.
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