Serum Levels of 3-Deoxyglucosone and Tissue Contents of Advanced Glycation End Products Are Increased in Streptozotocin-Induced Diabetic Rats with Nephropathy

Toshimitsu Niwa,Takashi Miyazaki,Tomoyuki Katsuzaki,Noriyuki Tatemichi,Yoshifumi Takei

Serum Levels of 3-Deoxyglucosone and Tissue Contents of Advanced Glycation End Products Are Increased in Streptozotocin-Induced Diabetic Rats with Nephropathy

1996

Toshimitsu Niwa
Takashi Miyazaki
Tomoyuki Katsuzaki
Noriyuki Tatemichi
Yoshifumi Takei

To investigate a role of the Maillard reaction in the pathogenesis of diabetic nephropathy, we measured serum levels of 3-deoxyglucosone (3-DG), a potent protein cross-linking intermediate of the Mail

Keywords:

Renal function
Endocrinology
Glycation
Internal medicine
Diabetic nephropathy
Maillard reaction
3-Deoxyglucosone
Nephropathy
Advanced glycation end-product
Streptozotocin
Medicine
Pathogenesis
Diabetes mellitus

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