Molecular-based allergy diagnostics in the real world: evidence for a cost explosion and an impact vacuum

Results MA testing has increased annually since its introduction in 2010. Spending on MA diagnostics exceeded £20,000 in 2013. Increases in test numbers were observed across a range of allergen groups during the time period and suggests routine ordering (Figure 1). Analysis of request sources indicated a surge in test numbers across 5 key user hospital units (Figure 2). Additionally, a marked increase in MA diagnostics orders from non-specialist sources was noted. Use of MA diagnostics introduced a mean increase in cost of 156% in adults (range 11%-900%) and 197% in children (range 9%-600%)(Table 1). Review of individual cases indicated that MA diagnostics had no specific impact on diagnosis or management in 78.6% of adults and 83.0% of children.