Total safety management through standardization of formulated ayurvedic Kajal using Eclipta alba and Vernonia cinerea herbs

Traditionally Kajal is known as Surma or Kohl which is used as an eye liner. Designing Ayurvedic Kajal with medicinal plants as a cosmetic product for beautification was thought of as a novel and an innovative technique. The main advantages of these cosmetic products are more patient compliance, water resistant property, stability and of course economical to formulate. Looking at that the present study was carried out with the aim of formulation of Ayurvedic Kajal with the help of two medicinal plants viz. Eclipta alba (EA) and Vernonia cinerea (VC) and evaluate their potential for sustained ocular delivery. Standardization of the herbs was performed based on different physiochemical parameters and revealed the values were within the prescribed limits. Ingredients used for this present investigation was standardized using TLC method whereas process standardization was carried out with organoleptic characters and was resulted similar characters in terms of color, odor and consistency. Furthermore product consistency was standardized by penetrometer test, moisture content test, TLC of the different extracts, microbial contamination and finally skin toxicity test. Different extracts like methanolic extract, lamp black extract, methanolic Kajal extract and hexane extracts for both the plants were carried out and revealed good results with all the extracts except World Scientific News 11 (2015) 32-44 -33hexane extract. Thereafter all the method revealed significant results without any allergic reaction when tested on New Zealand white strain rabbits. Hence the results concluded that the formulated Kajal with EA and VC is totally safe and can be used for novel cosmetic formulations.