Role of immune regulation in the early intervention of preeclampsia and its evaluation

The occurrence of preeclampsia and immune disorders have certain relations. Abnormal immune tolerance of maternal-fetal interface makes invasive trophoblast cells decrease and uterine spiral arteries of "recast obstacles" occur, leading to the formation of pathological placenta.There are various autoimmune abnormalities,for example,antiphospholipid antibody interferes with blood clotting and anticlotting factors,resulting in clotting disorders and placental micro thrombosis,which leads to decreased placental perfusion volume.Preeclampsia early intervention measures include:with risk factors,for pre-edampsia for pregnant women start taking low-dose aspirin in the middle trimester,which has a better preventive effect. During early and metaphase trimester of pregnancy,low-molecular weight heparin therapy also has a certain effect.The effect of various immune treatment and oxidation treatment lack evidence of evidence-based medicine.