Systemic Delivery of Cetrorelix to Rats by a New Aerosol Delivery System

Rosario Lizio,Thomas Klenner,Antonio Werner Sarlikiotis,Peter Romeis,Degenhard Marx,Thomas Nolte,Wolfgang Jahn,Gerrit Borchard,Claus-Michael Lehr

Systemic Delivery of Cetrorelix to Rats by a New Aerosol Delivery System

2001

Rosario Lizio
Thomas Klenner
Antonio Werner Sarlikiotis
Peter Romeis
Degenhard Marx
Thomas Nolte
Wolfgang Jahn
Gerrit Borchard
Claus-Michael Lehr

Purpose. To study the pulmonary absorption and tolerability of various formulations of the decapeptide cetrorelix acetate in rats by a new aerosol delivery system (ASTA-ADS) for intratracheal application.

Keywords:

Pulmonary Absorption
Cetrorelix
Aerosol
Gonadotropin RH
Dosage form
Pharmacology
Medicine
Tolerability
Pharmacokinetics
aerosol delivery
delivery system
pharmacology toxicology

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