Valuation of blood lactic acid level and lactate clearance rates in the prognosis of patients with shock

Objective To discuss the valuation of blood lactic acid level and lactate clearance rates in the prognosis of patients with shock.Methods We analyzed 75 patients with shock,divided them into the survival group and death group according to their condition after 7 days of admission.There were 44 patients in the survival group and 31 patients in the death group.Their blood lactate were measured when shock occurred,24 h after shock,48 h after shock and 72 h after shock.We calculated 6 h lactate clearance rate according to the formula [value of blood lactate when shock occured the value of blood lactate 6 hours after shock/value of blood lactate when shock occurs×100%].Results In death group,the blood lactate values were(7.3±1.4),(5.8±1.0),(3.8±0.5),(2.0±0.2) mmol/L,when shock occurred,24 h after shock,48 h after shock and 72 h after shock.The blood lactate values of death group when shock occurred,24 h after shock were significantly higher than that of the survival group,whose values were respectively(4.7±1.0),(2.8±0.7),the difference were significant(P0.05).The 6 h lactate clearance rate of death group was(6.7±2.7) mmol/L,significantly lower than that of survival group(29.8±10.4) mmol/L,and the difference was statistically significant.Conclusion The level of early blood lactate directly reflects the severity of shock.The lower the early lactate clearance rate is,the worse the prognosis of the patients.The combination of blood lactic acid level and lactate clearance rates could effectively assess the prognosis of patients with shock.