A phase II trial of topotecan and radiation therapy for CNS-metastases of patients with solid tumors

JAN-PETER HEDDE, M.D.,* THOMAS NEUHAUS, M.D., HEINRICH SCHULLER, M.D., UTE METZLER, M.D.,* INGO G. H. SCHMIDT-WOLF, M.D., ROLF KLEINSCHMIDT, M.D., CHRISTOPH LOSEM, M.D., OLIVER LANGE, M.D., CHRISTIAN GROHE, M.D., SEBASTIAN STIER, M.D., AND YON-DSCHUN KO, M.D. *Radiological Department, City Hospital of Merheim, Cologne, Germany; Johanniter-Hopsital, Bonn, Germany; Departments of Radiology and Internal Medicine I, University of Bonn, Bonn, Germany; and Medical Practice of Radiotherapy, Bonn-RheinSieg, Bonn, Germany