Ageing and Hepatic Steatosis Exacerbate Ischemia/ Reperfusion-Accelerated Outgrowth of Colorectal Micrometastases

Background Ischemia/reperfusion (I/R) injury is frequently encountered during hepatic surgery. We recently showed that I/R accelerates the outgrowth of pre-established colorectal micrometastases. The aim of this study was to assess the influence of ischemia time, gender, age, and liver steatosis on the accelerated outgrowth of colorectal metastases following I/R.