Derivatives (3-methylpyrrolidin-3-yl) methyl-pyridinyl ether and their use as antagonists of NK-3

Compound of formula: ** ** Formula wherein: A is selected from groups (a), (b) or (c): ** ** Formula or cycle alkyl, C1-8 alkyl optionally substituted with ( c) Ar1 is phenyl or a heteroaryl of six elements, X1 is N or CH, X2 is N-R1 or O, R1 is S (O) 2-C1-8 alkyl, C (O) -cycloalkyl substituted by C1 -8 or C (O) C1-8 alkyl, C1-8 alkyl, cyano, cycloalkyl or heteroaryl six membered substituted C1-8 alkyl, cyano, C (O) - C1-8 alkyl, halogen, C1-8 alkyl substituted with halogen or C1-8 alkoxy, or phenyl substituted with halogen or cyano, R2 is C1-8, halogen, pyrazolyl, 3-methyl- [1,2,4] oxazolyl, 5-methyl- alkyl [1,2,4] oxadiazol-3-yl, pyridyl substituted with cyano, or is phenyl sustistuido with halogen, or cyano, C1-8alkoxy or piperidin-2-one, or pharmaceutically active salts, stereoisomeric forms, including diastereoisomers and individual enantiomers of compound of formula I as well as racemic and non rac micas thereof.