Influence of feeding on metabolite excretion evidenced by urine 1H NMR spectral profiles : a comparison between subjects living in Rome and subjects living at arctic latitudes (Svaldbard)
1998
Abstract Urines from 25 normal subjects living in Rome and 25 normal subjects living in Ny-Alesund (Svaldbard) were analysed by 1HNMR spectroscopy. The observed differences in the concentration of the major metabolites were correlated to the composition of the diet. It was found that a diet rich of carbohydrates, such as the Italian diet, is respondible for an increased excretion of citrate, lactate, alanine, and glycine. Thus a correct diagnostical interpretation of urinary metabolites needs to consider feeding habits.
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