Diffuse cavitary lung lesions: reply to Marchiori et al.

Sir, We appreciate the comments of Marchiori et al. [1] and their recommendation for inclusion of benign neoplasm in the differential diagnosis of multiple cavitary lung lesions. Our case illustrates that coming to a correct diagnosis in this situation can be difficult [2]. Considering all diagnostic possibilities, including malignancy, early in the process it is important to allow steps to be taken to make a specific diagnosis and avoid delays in the initiation of the appropriate therapy. In the case we presented, PET/CT played an important role in guiding our choice of location to biopsy to obtain a definitive diagnosis. Earlier use of PET/CT may have led to a more rapid diagnosis. We agree that PET/CT, while it may provide clues, is not a specific diagnostic test and does not distinguish malignancy from alternative benign conditions.