Critique of the two-fold measure of prediction success for ratios: application for the assessment of drug-drug interactions
2011
Current assessment of drug-drug interaction (DDI) prediction success is based on whether predictions fall within a two-fold range of the observed data. This strategy results in a potential bias toward successful prediction at lower interaction levels [ratio of the area under the concentration-time profile (AUC) in the presence of inhibitor/inducer compared with control is
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
20
References
80
Citations
NaN
KQI