Time-dependent inactivation of steroid C17(20) lyase by 17β-cyclopropyl ether-substituted steroids
1996
Abstract Androstenes bearing a cyclopropyl group attached to the C-17β position with a heteroatom linker, designed as mechanism-based inhibitors of steroid C 17(20) lyase, were found to be potent, time-dependent inhibitors of this enzyme.
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