Abstract P248: Measures of Overall and Central Obesity and Cardiovascular Disease Risk Factors Among US Hispanic / Latino Adults: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Background: US Hispanics/Latinos have a high prevalence of obesity and related comorbidities. Few studies have compared different obesity measures and their associations with cardiovascular disease (CVD) risk factors in US Hispanic/Latino adults. Methods: We examined associations of six obesity measures (body mass index [BMI], fat mass index, and body fat percentage, waist circumference, waist-to-hip ratio [WHR], and waist-to-height ratio) with metabolic traits and CVD risk factors (hypertension, dyslipidemia and diabetes), among 9835 women and 6580 men from the HCHS/SOL, a population-based cohort of Hispanics/Latinos age 18-74 years from four US cities. Results: BMI was moderately correlated with WHR (r=0.37 in women; r=0.58 in men) and highly correlated with other obesity measures (r≥0.88 in women; r≥0.87 in men). The metabolic trait correlating most strongly with obesity measures was HOMA-IR (r≥0.34 in women; r≥0.45 in men), followed by triglycerides (r≥0.27 in women; r≥0.29 in men) and HDL-cholesterol...