Vectorial bicarbonate transport by Par-C10 salivary cells.

2+ - and cAMP-dependent stimulation. We identified Na+/H+ exchange, Na+-HCO3 - cotransport and anion exchange at the basolateral side of the cells as being involved in intracellular pH regulation and vectorial HCO3 - secretion. This cell line offers a good model for further studies to understand the molecular mechanisms of salivary HCO3 - secretion.