Response to Letters Regarding Article “Determinants of Surgical Outcome in Patients With Isolated Tricuspid Regurgitation”

We thank Drs Raikhelkar and Scurlock for their thoughtful review of our article.1 As pointed out, the pathogenesis of tricuspid regurgitation was functional late after left-sided valve surgery in most of our study subjects, and thus our findings may not be directly applicable in tricuspid regurgitation patients with other organic valve diseases. We agree that this is an important limitation of our study. However, because we prospectively enrolled consecutive patients, we believe our data represent the real patient population in tertiary referral center. Further long-term study is needed to determine predictors of …