Accurate analysis of genuine CRISPR editing events with ampliCan
2019
We present ampliCan, an analysis tool that unites identification, quantification and
visualization of genuine genome editing events from CRISPR amplicon sequencing
data. ampliCan overcomes methodological challenges suffered by other tools to
estimate the true mutational efficiency in a high-throughput automated fashion.
ampliCan controls for biases at every step of the analysis and generates reports that
allow users to quickly identify successful editing events or potential issues with their
experiments. We benchmarked ampliCan against other leading tools demonstrating
that it outperformed all in the face of common confounding factors.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
16
References
6
Citations
NaN
KQI