Noradrenaline up‐regulates volume‐regulated chloride current by PKA‐independent cAMP/exchange protein activated by cAMP pathway in human atrial myocytes

Background and Purpose Adrenergic regulation of cell volume‐regulated chloride current (ICl.vol) is species‐dependent. The present study investigates the mechanism underlying adrenergic regulation of ICl.vol in human atrial myocytes.