Abstract 16575: Synthetic TBX18 mRNA Induces Durable Reprogramming of Cardiac Myocytes to Pacemaker Cells

David Wolfson,Nadine Zureick,Natasha Fernandez,Jared Beyersdorf,Christina Sheng,Sung Jin Park,Philip J. Santangelo,Hee Cho

Abstract 16575: Synthetic TBX18 mRNA Induces Durable Reprogramming of Cardiac Myocytes to Pacemaker Cells

2020

David Wolfson
Nadine Zureick
Natasha Fernandez
Jared Beyersdorf
Christina Sheng
Sung Jin Park
Philip J. Santangelo
Hee Cho

Introduction: Adenoviral gene delivery of transcription factor, TBX18, has been proven to reprogram ordinary cardiomyocytes to pacemaker cells, and provide ventricular pacing in the rodent and porc...

Keywords:

Cell biology
Myocyte
Reprogramming
Messenger RNA
Medicine

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