Hepatoprotective Effect of Liv.52 and Kumaryasava on Carbon Tetrachloride induced Hepatic Damage in Rats

Oral administration of Liv.52 and Kumaryasava to carbon tetrachloride (CCl4) treated rats improved growth. Kumaryasava was more effective in reducing the liver weight increase due to hepatotoxicity of CCl4. Hepatic arginase, cathepsin-B, acid phosphatase, ribonuclease activity, which were decreased on CCl4 treatment was stimulated by both Liv.52 and Kumaryasava. Results indicate that Liv.52 and Kumaryasava have protective effect on hepatic enzyme induced due to CCl4 hepatotoxicity.