LONG TERM CLINICAL MORBIDITY AS A RESULT OF ANGIOMYOLIPOMA ASSOCIATED WITH TUBEROUS SCLEROSIS COMPLEX

INTRODUCTION AND OBJECTIVES: Nutritional status plays an important role in the outcomes of malignant diseases. Prognostic Nutritional Index (PNI) has been successfully used to predict outcomes in colo-rectal cancer, however no reports exist for its use in bladder cancer. This study aims to determine if PNI can predict the operative and oncological outcomes following robot-assisted radical cystectomy (RARC) in bladder cancer. METHODS: A retrospective comparative analysis of patients undergoing RARC was performed. PNI was measured using the serum albumin and absolute lymphocyte counts (PNI1⁄4 Albumin x 10 + LC x 0.005). Based on the preoperative PNI values, all patients were divided into 2 groups, (PNI > 50 normal and 50, while 131 belonged to PNI 50 group. (2.4 vs 2.6, p1⁄4 0.015). In terms of peri-operative outcomes, the PNI > 50 group was associated with shorter hospital stay (1.5 vs 2.6 days, p1⁄4 50 group, but this difference was not statistically significant. On the KM curve, the PNI> 50 group demonstrated a better metastasis free survival, than the PNI 50 is associated with shorter hospital stay and a better metastasis free survival following RARC. Multi-institutional studies will help better understand its use in comparing outcomes for radical cystectomy between minimally invasive and open approach.