Cardiovascular risk factors after Kawasaki disease: A case-control study *

Abstract Objectives: To determine cardiovascular risk profiles of patients with Kawasaki disease and to relate them to a noninvasive measure of endothelial function. Study design: Case-control study. Cardiovascular risk assessment including brachial artery reactivity was performed in 24 patients 11.3 ± 1.8 (mean ± SD) years after Kawasaki disease and in 11 subjects in a normal control group. Results: The case versus control groups were similar regarding age, sex, race, body mass index, and percentage of ideal body weight, although cases had a higher mean z score of body mass index than normal (+1.00 ± 1.18; P z score of triglyceride levels (+1.35 ± 2.04; P z scores (+0.76 ± 1.06; P P Conclusions: Patients after Kawasaki disease tend to have a more adverse cardiovascular risk profile potentially indicative of an increased predisposition to premature atherosclerotic changes. (J Pediatr 2001;138:400-5)