Synthesis of the trypsin fragment 10-25/75-88 of mouse nerve growth factor : II. The unsymmetrical double chain cystine peptide

The synthesis of the unsymmetrical double chain cystine peptide corresponding to sequence 10-25/75-88 of mouse nerve growth factor is described. The synthetic product was inactive in all bioassays examined; consequently, this portion of the NGF molecule did not represent or contain a lower molecular weight form of the neurotrophic factor.