LDL CHOLESTEROL REDUCTION WITH BMS-962476, AN ADNECTIN INHIBITOR OF PCSK9: RESULTS OF A SINGLE ASCENDING DOSE STUDY

BMS-962476 is an anti-human proprotein convertase subtilisin/kexin type 9 (PCSK9) Adnectin-based protein therapeutic formatted with 40 kDa branched polyethylene glycol being developed to prevent PCSK9-LDL receptor binding and reduce LDL cholesterol (LDL-C). We report safety, tolerability and