Abstract 14216: Myocyte-Specific Gene Targeting and RNASeq Reveal a Selective Requirement for P300 For Basal Expression of Myh7 and the Induction of Cardiac Hypertrophy After Pressure Overload

Background: Acetyltransferase p300 is required for cardiac myocyte-specific gene expression and embryonic growth, and is induced by stress in the adult heart. Objective: To determine the functional...