Detection of Nanoparticle Endocytosis Using Magneto- Photoacoustic Imaging

and targeted therapy, [ 3 ] for their ubiquitous tissue accessibility, large surface-area-to-volume ratios, and functional versatility. [ 1–4 ] In biological applications, delivering nanoparticles to the tissues of interest is a fi rst critical step. [ 5 ] The delivered nanoparticles can then interact readily with living cells. Cellular endocytosis of nanoparticles—an important manifestation of the cell–nanoparticle interaction—can infl uence the associated diagnostic sensitivity and therapeutic effi ciency. [ 4 ]