Inhibitory Activities of Kojyl Thioether Derivatives against Nitric Oxide Production Induced by Lipopolysaccharide

Ho Sik Rho,Dae Sung Yoo,Soo Mi Ahn,Myung Kyoo Kim,Dong Ha Cho,Jae Youl Cho

Inhibitory Activities of Kojyl Thioether Derivatives against Nitric Oxide Production Induced by Lipopolysaccharide

2010

Ho Sik Rho
Dae Sung Yoo
Soo Mi Ahn
Myung Kyoo Kim
Dong Ha Cho
Jae Youl Cho

A series of kojic acid thioether derivatives (I), their sulfoxides (II), and sulfones (III) are synthesized and evaluated for inhibitory activity against NO production in LPS-activated macrophages.

Keywords:

Kojic acid
Lipopolysaccharide
Thioether
Nitric oxide
Inhibitory postsynaptic potential
Biochemistry
Chemistry
Organic chemistry
no production

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