Compositions based on methyl-cyclodextrin for the treatment and / or prevention of diseases by increasing HDL-cholesterol levels

The present invention relates to a new use of a pharmaceutical composition comprising at least a methyl-cyclodextrin having a degree of molar substitution (MS) between 0.05 and 1.5 in the treatment and / or prevention of diseases which to be treated and / or prevented by an increase in HDL-cholesterol. It also relates to its use in the treatment and / or prevention of atherosclerosis, or complications related to atherosclerosis, Alzheimer's disease or Niemann-Pick type C. The pharmaceutical compositions of the invention can also be used to promote further reduction in triglycerides and circulating fatty acids and reduce or prevent atherosclerotic plaques.