Hipertensión arterial pulmonar asociada a esclerodermia en mestizos mexicanos

Introduction. The diagnosis of pulmonary arterial hypertension (HAP) in esclerodermia (SSc) is not made of early way, which is significant since this complication is one of the main causes of mortality and morbidity in SSc. In the Mexican mestizo the prevalence of HAP is not known. Material and methods. Clinical, non-experimental, cross-sectional and opened, in patients with SSc, carrying out echocardiogram Doppler color (ECD), tests of respiratory function (PFR), anticentromere determination of antibodies (AAC) and antitopoisomerase (AAT). Analyzing prevalence of the HAP, correlation between the time of evolution of SSc and it is present at (Yes/No) of HAP with test χ2, the relation between time of evolution of SSc and values of the systolic pressure of the pulmonary artery (PSAP), relation between HAP and the fraction of expulsion of the left ventricle (FEVI), statistical program used IBM SPSS version 20. Results. We included 35 patients, the associated diffuse variety to the AAC is observed most frequently, not showing positive correlation with HAP. The PFR show pulmonary commitment in the 68.8% of the cases, without correlation with HAP, by ECD the prevalence of HAP is documented in 34.3% of the cases, with PSAP > 36 mmHg, the time of evolution of the disease and the PSAP shows positive correlation (0.569). Conclusions. The prevalence of HAP in the Mexican mestizo with SSc is significant, our results suggest the ECD must be including within the initial protocol and subsequent evaluation of the patients with this pathology.