High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody-Drug Conjugate Libraries.

Sayumi Yamazoe,Jason M. Hogan,Sean M. West,Xiaodi A. Deng,Srikanth Kotapati,Xiang Shao,Patrick G. Holder,Vandana Lamba,Mary Huber,Cong Qiang,Sanjeev Gangwar,Chetana Rao,Gavin Dollinger,Arvind Rajpal,Pavel Strop

High-Throughput Platform to Identify Antibody Conjugation Sites from Antibody-Drug Conjugate Libraries.

2020

Sayumi Yamazoe
Jason M. Hogan
Sean M. West
Xiaodi A. Deng
Srikanth Kotapati
Xiang Shao
Patrick G. Holder
Vandana Lamba
Mary Huber
Cong Qiang
Sanjeev Gangwar
Chetana Rao
Gavin Dollinger
Arvind Rajpal
Pavel Strop

ABSTRACT: Antibody-drug conjugates (ADCs) are a therapeutic modality that traditionally enable the targeted deliv-ery of highly potent cytotoxic agents to specific cells such as tumor cells. More r...

Keywords:

Cytotoxicity
Antibody-drug conjugate
Antibody
Biochemistry
Conjugate
Chemistry
tumor cells

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations