Association between the immune responses against Helicobacter pylori infections and the concentration of atrophic gastric biomarkers in Cameroon

Gastric colonization by Helicobacter pylori causes recruitment of inflammatory cells by the adherence of bacteria to the epithelium and the release of virulence factors. Gastritis induces disruption of acid secretion depending on the predominant location in the stomach, antrum or corpus. The purpose of this study was to examine the impact of the presence of H. pylori on acid secretion and to establish relationship between the level of immune responses against H. pylori and gastric biomarkers in patient with dyspeptic disorders. Methods: From march to July 2011, all patients with dyspeptic underwent upper gastro-intestinal tract endoscopy with biopsy at the Yaounde Central Hospital and