Alterations detected by 1H MRS and MRI in a preclinical model of ovarian cancer treated with a phosphatidylcholine-specific phospholipase C inhibitor are associated with downmodulation of HER2 expression and reduced in vivo tumor growth

R. Ganm\ A. Ricc\, M.E. Pisanu\ L Paris\ L Altabella\ E. Surrentino\ M. Sagnoli2, L Uliac3, A. Granata2, S. Canevari2, D. Mezzanzanica2, E. lo11o1, F. Podo1 1Ce/18iology and Neurosciences Dept, Istituto Superiore di Sanita, Rome, ltaly 2Experimental Oncology and Molecu/ar Medicine Dept, Fondazione JRCCS Istituto Nazionale dei Tumori, Milan, ltaly 3Morphofunctiona/ SciencesHistology Dept University of Medicine and Pharmacy, /asi, Romania