Histone reader BRWD1 targets and restricts recombination to the Igk locus.
2015
V(D)J recombination is developmentally regulated and occurs at restricted sites within the genome. Clark and colleagues show that the histone reader BRWD1 is required for precise positioning of nucleosomes and targeting of RAG recombinase proteins within the Igk locus.
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- Machine Reading By IdeaReader
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