In Vitro Blood Compatibility of Alumina Coatings Prepared by Micro-Arc Oxidation on Biomedical NiTi Alloy

In this paper, the in vitro blood compatibility of micro-arc oxidation (MAO) alumina coatings prepared in different times on biomedical NiTi alloy was studied using hemolysis ratio, dynamic blood clotting and platelet adhesion. The results show that the blood compatibility of the coated NiTi alloy is much better than that of uncoated NiTi alloy and reduces with increasing the micro-arc oxidation treatment times. Therefore, it can be concluded that the blood compatibility of materials is mainly dominated by the surface species contacted with blood within some ranges of surface roughness, not the surface morphologies, and the MAO alumina coatings can effectively improve the blood compatibility of NiTi alloy