Gallium enolate-mediated intermolecular aldol reaction and addition reaction of alpha-bromoketone with imine

Treatment of alpha-bromoketone with gallium triiodide or methyl galliumiodide prepared in situ provides gallium enolates which react with carbonyl compounds or imines to give beta - hydroxy ketones or beta -phenylamino ketones effectively in moderate yields (C) 1998 Elsevier Science Ltd. All rights reserved.