Treatment-adherence beliefs and behaviors in patients with chronic myeloid leukemia (CML).

9558 Background: Tyrosine kinase inhibitors (TKIs) are effective yet chronic indefinite therapy for CML. Strong links exist between TKI adherence and optimal outcomes. Suboptimal adherence is common, affecting clinical outcomes and healthcare costs. Nonadherent patients underrecognize missed-dose impact on response. This study explored the link between belief and behavior vis-a-vis adherence. Methods: With outreach to online, national and community networks from 10/13 to 7/14, 484 CML patients enrolled in the Cancer Experience Registry: CML, an online project to advance CML knowledge and patient engagement. 393 (81%) completed a web-based survey including questions assessing accord with 2 statements (1) It is okay to miss a dose of my CML medicine every now and then, and (2) I need to take every dose of my CML medicine or it might not work; as well, participants reported missed TKI-dose frequency. Logistic regression was used to study the beliefs-behavior link among US patients taking TKIs (n = 318). Regr...