In vivo Histomorphological Evaluation of Geopolymer-CarbonatedApatite Nanocomposites Implanted on Rabbit Tibiaat Early Bone Healing

Dental implants have become more desirable treatment for replacing missing teeth. The mechanical properties and biocompatibility of titanium and zirconia are excellent but they are less bioactive. The chemical composition of the carbonate apatite is similar to enamel and dentin. Geopolymers are inorganic polymers and they are similar to ceramics, they have an excellent mechanical properties, bioactivity, biocompatibility.The purpose of this study is to assess the early bone healing in osseointegration at geopolymer-carbonated apatite (CHA) nanocomposites. Methods: Geopolymer- CHA nanocomposites with diameter of 3 mm and length of 6 mm is placed in tibia of eight male New Zealand White rabbit whose body weight is 3 to 3.5 kg and 6 month ages. Experimental subjects were randomly assigned to 2 groups for assessing the bone healing capability around samples to 14 and 28 days histomorphologically. Wilcoxon test was performed and p <0.05 was considered significant, using Minitab software version 13. Results: Granulation tissue, woven, and lamellar bone were analyzed. In the 14th day revealed a reactive bone formation. Osteoblasts, osteoids, and osteocytes showed more mature and woven bone became denser on the 28th day. Conclusion: Geopolymer-CHA nanocomposites could be considered as a potential dental implant material from mechanical and biological properties point of view.