ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction

Raquel de Oliveira,Tamiris Invencioni Moraes,Alvaro Cerda,Mario Hiroyuki Hirata,Cristina Moreno Fajardo,Marcela Correia Sousa,Egidio Lima Dorea,Márcia Martins Silveira Bernik,Rosario Dominguez Crespo Hirata

ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction

2015

Raquel de Oliveira
Tamiris Invencioni Moraes
Alvaro Cerda
Mario Hiroyuki Hirata
Cristina Moreno Fajardo
Marcela Correia Sousa
Egidio Lima Dorea
Márcia Martins Silveira Bernik
Rosario Dominguez Crespo Hirata

Background Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6 (IL6) have been associated with adiposity and obese-related phenotypes. This study investigated the relationship of ADIPOQ and IL6 gene polymorphisms with pro-inflammatory and cardiometabolic markers in obese patients.

Keywords:

Insulin resistance
Obesity
Adiponectin
Gene polymorphism
Interleukin 6
Body weight
Medicine
Endocrinology
Internal medicine
Leptin
Type 2 diabetes
Dyslipidemia
Adipokine

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