Development of great burdock essence compounds

Abstract The nanomicelle encapsulating the water-insoluble substances can solubilize in aqueous solution. In this study, we used nanomicelle technology to develop great burdock essence. Black semen oil extracts of Arnebia euchroma and Angelica sinensis , water extract of Arctium lappa , phospholipid, and glycerol were mixed and homogenized in a high-pressure homogenizer. The particle size of great burdock essence was 167.1 ± 0.96 nm. Concentrations of chlorogenic acid, shikonin, and ferulic acid of great burdock essence were 2.300 ± 0.605, 1.484 ± 0.009, and 1.463 ± 0.006 μg/g, respectively. The great burdock essence had nanoparticle-size molecules, which resulted in easy cellular uptake by endocytosis, and main components of three herbs. However, for more information on the health benefits of the great burdock essence, further studies are needed.