Dithiocarbamates as an Efficient Intermediate for the Synthesis of Symmetrical Substituted 2,5-Diamino-1,3,4-thiadiazoles in Water

Synthesis of symmetrical substituted 2,5-diamino-1,3,4-thiadiazoles is described. Reaction of easily prepared dithiocarbamates with hydrazine gives the corresponding thiadiazoles in moderate to good yields. This method is new, efficient, and simple especially in the work-up procedure.