FROPOFOL PREVENTS DISEASE PROGRESSION IN HYPERTROPHIC CARDIOMYOPATHY

Increased contractility by the myofilaments themselves is recognized as a crucial factor in the pathogenesis of hypertrophic cardiomyopathy (HCM). In this study, we test the hypothesis that fropofol (a propofol derivative with no anesthetic activity), is a direct myofilament depressing agent that