Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation

Induction chemotherapy followed by concomitant radiotherapy and weekly cisplatin versus the same concomitant chemoradiotherapy in patients with nasopharyngeal carcinoma: a randomized phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG) with biomarker evaluation G. Fountzilas*, E. Ciuleanu, M. Bobos, A. Kalogera-Fountzila, A. G. Eleftheraki, G. Karayannopoulou, T. Zaramboukas, A. Nikolaou, K. Markou, L. Resiga, D. Dionysopoulos, E. Samantas, H. Athanassiou, D. Misailidou, D. Skarlos & T. Ciuleanu Department of Medical Oncology, ‘‘Papageorgiou’’ Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece; Department of Radiation Oncology, ‘‘Ion Chiricuta’’ Cancer Institute, Cluj, Romania; Laboratory of Molecular Oncology, Hellenic Foundation for Cancer Research, Aristotle University of Thessaloniki School of Medicine, Thessaloniki; Department of Radiology ‘‘AHEPA’’ Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki; Section of Biostatistics, Hellenic Cooperative Oncology Group, Data Office, Athens; Department of Pathology, Aristotle University of Thessaloniki School of Medicine, Thessaloniki; Department of Otorinolaryngology, ‘‘AHEPA’’ Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki; Department of Pathology, ‘‘Ion Chiricuta’’ Cancer Institute, Cluj, Romania; Third Department of Medical Oncology, ‘‘Agii Anargiri’’ Cancer Hospital, Athens; Department of Radiation Oncology, ‘‘Agii Anargiri’’ Cancer Hospital, Athens; Department of Radiation Oncology, ‘‘Papageorgiou’’ Hospital, Aristotle University of Thessaloniki School of Medicine, Thessaloniki; Second Department of Medical Oncology, ‘‘Metropolitan’’ Hospital, Piraeus, Greece; Department of Medical Oncology, ‘‘Ion Chiricuta’’ Cancer Institute, Cluj, Romania