2,6,8,12-tetraoxa-4,10(1,4)-dibenzena-1,7(2,7)-difluorenacyclododecaphane-19,79-dione- : A new macrocyclic receptor for polar organic molecules

The results of computer-assisted molecular modeling showed that 2,6,8,12-tetraoxa-4,10(1,4)-dibenzena-1,7(2,7)-difluorenacyclododecaphane-19,79-dione is promising as a receptor for polar organic molecules. This compound was synthesized by the reaction of 1,4-bis(bromomethyl)benzene with 2,7-dihydroxyfluoren-9-one in DMF in the presence of anhydrous potassium carbonate under strong dilution. Crystalline complexes of the title compound with DMF and nitrobenzene were isolated and studied by X-ray diffraction. In both complexes the substrate is located in the ligand cavity.