Technical realization of an experimental model of the resonance mechanism of activation of oxygen transport and consumption by hepatocytes

1. Different oscillatory regimes in the dynamics of consumption of oxygen as a substrate by hepatocytes are found at different operating frequencies of the HLM, which agrees well with the concept of cell clocks presented in [13]. The rhythm of operation of these clocks as open polyenzymatic systems depends on the dynamics of the fluctuations of the rate of arrival of the substrate, in the given case oxygen, at the input of these systems.